Disrupted social development enhances the motivation for cocaine in rats
نویسندگان
چکیده
منابع مشابه
the search for the self in becketts theatre: waiting for godot and endgame
this thesis is based upon the works of samuel beckett. one of the greatest writers of contemporary literature. here, i have tried to focus on one of the main themes in becketts works: the search for the real "me" or the real self, which is not only a problem to be solved for beckett man but also for each of us. i have tried to show becketts techniques in approaching this unattainable goal, base...
15 صفحه اولefl teachers job satisfaction and social capital in relation to students’ motivation
abstract this mixed method study examines whether there is any relationship among the variables of the study (job satisfaction, social capital and motivation). the researcher considered job satisfaction and social capital as independent variables; motivation is the dependent variable of the study. the researcher applied a questionnaire to assess each variable. to measure efl teachers’ job sati...
VTA BDNF enhances social stress-induced compulsive cocaine bingeing
Every day in the United States, 120 people die as a result of drug overdose, a rate that has more than doubled from 1999 to 2013 [1]. The degree of vulnerability to addiction is determined by the interaction between genetic and environmental factors. Social stress is an environmental factor some experience on a daily basis (e.g., domestic abuse, bullying, work-related issues, etc.). Since peopl...
متن کاملRepeated Cocaine Exposure Facilitates the Expression of Incentive Motivation and Induces Habitual Control in Rats
There is growing evidence that mere exposure to drugs can induce long-term alterations in the neural systems that mediate reward processing, motivation, and behavioral control, potentially causing the pathological pursuit of drugs that characterizes the addicted state. The incentive sensitization theory proposes that drug exposure potentiates the influence of reward-paired cues on behavior. It ...
متن کاملReinforcement-related regulation of AMPA glutamate receptor subunits in the ventral tegmental area enhances motivation for cocaine.
Chronic cocaine use produces numerous biological changes in brain, but relatively few are functionally associated with cocaine reinforcement. Here we show that daily intravenous cocaine self-administration, but not passive cocaine administration, induces dynamic upregulation of the AMPA glutamate receptor subunits GluR1 and GluR2 in the ventral tegmental area (VTA) of rats. Increases in GluR1 p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Psychopharmacology
سال: 2013
ISSN: 0033-3158,1432-2072
DOI: 10.1007/s00213-013-3362-8